Tools for analyzing cell shape changes during chemotaxis
نویسندگان
چکیده
منابع مشابه
Cell shape changes during gastrulation in Drosophila.
The first morphogenetic movement during Drosophila development is the invagination of the mesoderm, an event that folds a one-layered epithelium into a multilayered structure. In this paper, we describe the shape changes and behaviour of the cells participating in this process and show how mutations that change cell fate affect this behaviour. We divide the formation of the mesodermal germ laye...
متن کاملDynamic force balances and cell shape changes during cytokinesis.
During the division of animal cells, an actomyosin ring is formed in the cell cortex. The contraction of this ring induces shape changes of the cell and the formation of a cytokinesis furrow. In many cases, a cell-cell interface forms that separates the two new cells. Here we present a simple physical description of the cell shape changes and the dynamics of the interface closure, based on forc...
متن کاملRho-kinase Controls Cell Shape Changes during Cytokinesis
BACKGROUND Animal cell cytokinesis is characterized by a sequence of dramatic cortical rearrangements. How these are coordinated and coupled with mitosis is largely unknown. To explore the initiation of cytokinesis, we focused on the earliest cell shape change, cell elongation, which occurs during anaphase B and prior to cytokinetic furrowing. RESULTS Using RNAi and live video microscopy in D...
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Essential life processes are heavily controlled by a variety of positive and negative feedback systems. Cytokinesis failure, ultimately leading to aneuploidy, is appreciated as an early step in tumor formation in mammals and is deleterious for all cells. Further, the growing list of cancer predisposition mutations includes a number of genes whose proteins control mitosis and/or cytokinesis. Cyt...
متن کاملTools for Developing and Analyzing Parallel For
PYRROS is a tool for scheduling and parallel code generation for distributed memory message passing architectures [35]. In this paper, we discuss several compile-time optimization techniques used in PYRROS. The scheduling part of PYRROS optimizes both data and program mapping so that the parallel time is minimized. The communication and storage optimization part facilitates the generation of e ...
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ژورنال
عنوان ژورنال: Integrative Biology
سال: 2010
ISSN: 1757-9694,1757-9708
DOI: 10.1039/c0ib00036a